Microbes identified in fecal samples from 160 Japanese centenarians with an average age of 107 were analyzed by a team of researchers from the Broad Institute of MIT and Harvard.
According to the research, centenarians have higher amounts of bacterial species that produce secondary bile acids than younger people.
These bile acids are thought to protect the intestines and control immunological responses in the body.
The growth of an antibiotic-resistant bacterium that causes severe diarrhea and gut inflammation was greatly prevented by one molecule (isoalloLCA).
The researchers also discovered that isoalloLCA effectively suppressed or killed a variety of different gram-positive infections, implying that it may aid the body in maintaining the delicate balance of microbial populations in a healthy gut.
These discoveries may aid researchers in the development of new treatments for chronic inflammation and bacterial illness.
Source: BROAD Institute